Cancer cells typically hide from the immune system by displaying minimal recognizable proteins. However, in this new study, researchers disrupted protein production within the cancer cells, forcing them to produce abnormal proteins.
These new proteins made the cancer cells more visible to the immune system, prompting a stronger immune response capable of targeting and destroying them.
In tests using mouse models, the method successfully activated immune cells to target and inhibit tumor growth.
When combined with existing immunotherapy treatments, the approach led to the complete eradication of tumors in approximately 40 percent of the mice, according to Yardena Samuels, who led the research.
This innovative technique holds significant promise for improving cancer treatment, particularly for cancers with fewer mutations.
The research team is now investigating how the method can be applied to various other cancers, including breast, pancreatic, and colorectal cancers, hoping it will lead to more effective, widespread therapies in the future.
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