The accident took place in Abu Sifin church in the Imbaba neighborhood, according to the ministry.
"Four of those injured are in unstable conditions," the ministry said in a statement, adding it had sent 37 ambulances to the scene.
The fire started from an air conditioner on the second floor of the church building because of an electrical fault, the Egyptian Interior Ministry said in a separate statement.

Fire fighters work at a fire site in Giza Province, Egypt, on Aug. 14, 2022. (Ministry of Interior Affairs of Egypt/Handout via Xinhua)
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